Journal: Eur J Epidemiol
Lead Author: Galleoti, et al.
Original date of publication: 05/01/2013
Link: https://pubmed.ncbi.nlm.nih.gov/23543123/
Keywords: childreneffectivenessfluGuillian-Barre syndromeinfluenzaItalyseasonal influenza vaccinevariants
Full Author List: Francesca Galeotti 1, Marco Massari, Roberto D'Alessandro, Ettore Beghi, Adriano Chiò, Giancarlo Logroscino, Graziella Filippini, Maria Donata Benedetti, Maura Pugliatti, Carmela Santuccio, Roberto Raschetti; ITANG study group
Lead Author: Galleoti, et al.
Original date of publication: 05/01/2013
Link: https://pubmed.ncbi.nlm.nih.gov/23543123/
Summary Context
This powerful study uses two methods to conclude that GBS is associated with seasonal flu vaccination.
Comments
Guillain-Barré Syndrome (GBS) is an acute acquired immune-mediated polyradiculoneuropathy, and researchers found this condition was 3.8 times as likely after vaccination with influenza vaccine. When researchers looked at only neurological centers reporting high quality data, they found an odds ratio of 4.9 for GBS and vaccination (5x likelihood of developing GBS)
Abstract or Results, Key Passages
“The case-series analysis (based on cases only) also confirms the association between this vaccination and GBS (RR = 2.1). “”Main strengths of this study are that it is large and statically powerful.”
Keywords: childreneffectivenessfluGuillian-Barre syndromeinfluenzaItalyseasonal influenza vaccinevariants
Full Author List: Francesca Galeotti 1, Marco Massari, Roberto D'Alessandro, Ettore Beghi, Adriano Chiò, Giancarlo Logroscino, Graziella Filippini, Maria Donata Benedetti, Maura Pugliatti, Carmela Santuccio, Roberto Raschetti; ITANG study group
