Journal: Clin Infect Dis.
Lead Author: McLean et al.
Original date of publication: 11/15/2014
Link: https://pubmed.ncbi.nlm.nih.gov/25270645/
Keywords: effectivenessfluinfluenzaseasonal influenza vaccine
Full Author List: Huong Q McLean, Mark G Thompson , Maria E Sundaram, Jennifer K Meece, David L McClure, Thomas C Friedrich, Edward A Belongia
Lead Author: McLean et al.
Original date of publication: 11/15/2014
Link: https://pubmed.ncbi.nlm.nih.gov/25270645/
Summary Context
This study shows that vaccinating every year leads to lower efficacy with subsequent flu shots.
Comments
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This study noted that being vaccinated in prior years reduces the value of future flu vaccinations. In other words, repeated vaccination is counter productive in certain aspects with the seasonal flu vaccine.
Abstract or Results, Key Passages
“In the analysis using 5 years of historical vaccination data, current season (vaccine efficacy) VE against H3N2 was significantly higher among vaccinated individuals with no prior vaccination history (65%; 95% confidence interval [CI], 36%-80%) compared with vaccinated individuals with a frequent vaccination history (24%; 95% CI, 3%-41%; P = .01). “
Keywords: effectivenessfluinfluenzaseasonal influenza vaccine
Full Author List: Huong Q McLean, Mark G Thompson , Maria E Sundaram, Jennifer K Meece, David L McClure, Thomas C Friedrich, Edward A Belongia
