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A case of metastatic breast carcinoma to the skin expressing SARS-CoV-2 spike protein possibly derived from mRNA vaccine

Journal: Journal of Dermatological Science
Lead Author: Shigetoshi Sano
Original date of publication: 10/03/2025
Link: https://www.jdsjournal.com/article/S0923-1811(25)00180-X/abstract#supplementary-materiall

Summary Context

This study found a woman whose cancer was in remission but after her sixth mRNA shot, spike protein was found in her carcinoma.

Comments

This study used genetic testing of a carcinoma (tumor) and found what appeared to be vaccine-specific genetic fragments (no necleocapsid) of the spike protein. This patient had 6 mRNA injections.

Abstract or Results, Key Passages

From a third party review by Hulscher as the original is behind paywall, on potential implications: “Genomic integration of vaccine-derived mRNA or contaminant DNA fragments in host cells.Immune tolerance induction via spike-driven PD-L1 upregulation and Type I interferon suppression, impairing anti-tumor immunity.Estrogen receptor modulation by spike protein, potentially accelerating breast and ovarian cancer proliferation.


Keywords: Metastatic skin cancerBreast carcinomaPagetoid cellSARS-CoV-2 spike proteinmRNA vaccine
Full Author List: Shigetoshi Sano