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Real world effectiveness of antipneumococcal vaccination against pneumonia in adults: a population-based cohort study, Catalonia, 2019

Journal: BMC Infect Dis
Lead Author:
Original date of publication: 10/01/2025
Link: https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-025-11596-w

Summary Context

This study looked at over 2 million residents of Catalonia, Spain, and found not only no benefit from pneumococcal vaccination, but even higher rates of pneumonia.

Comments

This large epidemiological retrospective study looked at the effectiveness of pneumococcal vaccination and found it had no beneficial effect on rates, and even resulted in higher chances of acquiring pneumococcol pneumonia.

Abstract or Results, Key Passages

“This study did not find evidence of the clinical effectiveness of PPsV23/PCV13 vaccination in preventing the outcomes measured at population-based level. At present, new extended-valency, PCVs (PCV15/PCV20/PCV21) have been marketed for using in adults and, logically, vaccines’ effectiveness must be re-evaluated in the coming years.”


Keywords: adverse eventseffectivenessobservational studyPCVPneumococcal
Full Author List: Cinta de Diego-Cabanes, Verònica Torras-Vives, Angel Vila-Córcoles, Eva M. Satué-Gracia, M. José Forcadell-Peris, Frederic Gómez-Bertomeu, Leonardo de Esteban-Júlvez, Imma Hospital-Guardiola, Cruz M. Fuentes-Bellido, Anna Ribes-Alcover, Clara Rodriguez-Casado & Olga Ochoa-Gondar