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Human papillomavirus vaccination of adult women and risk of autoimmune and neurological diseases

Journal: J Intern Med
Lead Author: Hviid A., et al.
Original date of publication: 02/01/2018
Link: https://pubmed.ncbi.nlm.nih.gov/29044769/

Summary Context

This study shows that many women can develop celiac disease after HPV vaccination, very pro-vaccine authors try to explain away but admit statistical significance of the findings.

Comments

This review by very pro-vaccine scientists (lead author paid by HPV manufacturers) nonetheless found statistically signficant increase in celiac disease among those who received the quadrivalent HPV vaccine. There were other safety signals with statistical significance early in the paper development but all these but celiac disease were removed after applying various new criteria statistically. The rate of celiac disease in the vaccinated group was 31 per 100,000 and 13.9 in the unvaccinated group.

Abstract or Results, Key Passages

” We identified seven adverse events with statistically significant increased risks following vaccination-Hashimoto’s thyroiditis, coeliac disease, localized lupus erythematosus, pemphigus vulgaris, Addison’s disease, Raynaud’s disease and other encephalitis, myelitis or encephalomyelitis. After taking multiple testing into account and conducting self-controlled case series analyses, coeliac disease (RR 1.56 [95% confidence interval 1.29-1.89]) was the only remaining association.


Keywords: Addison's diseaseadverse eventsceliac diseaseencephalitisHPV vaccinehuman papilloma viruslupusRaynaud's disease
Full Author List: A Hviid, H Svanström, N M Scheller, O Grönlund, B Pasternak, L Arnheim-Dahlström