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Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients

Journal: International Journal of Cardiology
Lead Author: Abbate et al
Original date of publication: 10/01/2021
Link: https://www.sciencedirect.com/science/article/pii/S0167527321012286?utm_source=substack&utm_medium=email

Summary Context

Case study of two adults suddenly presenting with fulminant (very severe and sudden) heart damage

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Both cases presented features of fulminant myocarditis with a temporal association with the BNT162b2 mRNA Covid-19 vaccination, in absence of other apparent causes, and with unique features of systemic hyperinflammation associated with refractory shock.

Abstract or Results, Key Passages

“Fulminant myocarditis may occur following SARS-CoV2 mRNA vaccination requiring mechanical cardiac support.•It is important to recognize features of systemic hyperinflammatory syndrome following SARS-CoV2 mRNA vaccination.”


Keywords: adverse eventsCardiac eventscovid vaccinemRNAmyocarditis
Full Author List: Antonio Abbate, Josh Gavin, Nima Madanchi, Christin Kim, Pranav R. Shah, Katherine Klein, Julie Boatman, Charlotte Roberts, Seema Patel, Stamatina Danielides b