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Evidence of Increase in Mortality After the Introduction of Diphtheria-Tetanus-Pertussis Vaccine to Children Aged 6-35 Months in Guinea-Bissau: A Time for Reflection?

Journal: Front Public Health
Lead Author: Aaby, et al.
Original date of publication: 03/01/2019
Link: https://pubmed.ncbi.nlm.nih.gov/29616207/

Summary Context

This paper in 2019 found troubling signals in which DTP-vaccinated children were significantly less likely to survive compared to those who didn’t receive it. Girls in that category were almost three times more likely to die.

Comments

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Even though kids that receive DTP have better nutritional status and had alleged protection against these diseases, their all cause mortality was higher than those that did not receive it.

Abstract or Results, Key Passages

“Although having better nutritional status and being protected against three infections, 6-35 months old DTP-vaccinated children tended to have higher mortality than DTP-unvaccinated children. All studies of the introduction of DTP have found increased overall mortality.”

Keywords: adverse eventschildrendeathdiptheriaDTP vaccinemortalitypertussistetanus
Full Author List: Peter Aaby, Søren Wengel Mogensen, Amabelia Rodrigues, Christine Benn