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COVID-19 vaccines and autoimmune disorders: A scoping review

Journal: AIMS Medical Science
Lead Author: Chaufan et al.
Original date of publication: 11/21/2025
Link: https://www.aimspress.com/article/doi/10.3934/medsci.2025023

Summary Context

This high level study looked at all kinds of studies on auto-immune reactions after mRNA vaccination. these showed people with pre-existing issues had flares, and new onsets reported of multiple sclerosis, lupus, type 1 diabetes, rheumatoid arthritis, Graves’ disease, Hashimoto’s thyroiditis, and other conditions.

Comments

Meta-analysis of over 100 studies of auto-immune responses after covid-19 vaccination. “Across 109 included studies, relapses or flares in patients with autoimmune disorders were reported in nearly 60% of studies, while about one-quarter described new-onset autoimmune disorders in persons without prior autoimmunity.”

Abstract or Results, Key Passages

“This review highlights the substantial patterns of reported associations of autoimmune disorders following COVID-19 vaccination, in patients with and without prior autoimmunity. The general and population-specific benefits of vaccination are claimed, but evidence for them is lacking. A proper evaluation of risks and benefits is needed to support vaccination recommendations given the reported associations between it and autoimmune disorders.”


Keywords: adverse eventsautoimmunitycovid vaccinatinmRNA
Full Author List: Claudia Chaufan, Laurie Manwell, Camila Heredia, Jennifer McDonald