Journal: J Infect Dis
Lead Author: Skowronski, et al.
Original date of publication: 10/04/2017
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC5853508/
Keywords: effectivenessfluinfluenzaseasonal influenza vaccinevariants
Full Author List: Danuta M Skowronski, Catharine Chambers, Suzana Sabaiduc, Gaston De Serres, Anne-Luise Winter, James A Dickinson, Jonathan B Gubbay, Steven J Drews, Christine Martineau, Hugues Charest, Mel Krajden, Nathalie Bastien, Yan Li
Lead Author: Skowronski, et al.
Original date of publication: 10/04/2017
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC5853508/
Summary Context
Influenza effectiveness findings may require consideration of other agent-host and immuno-epidemiologic influences on vaccine performance beyond antigenic match, including viral genomic variation, repeat vaccination, birth (immunological) cohort effects, and potential within-season waning of vaccine protection.
Comments
This study examined yet more failed results in seasonal flu vaccination, and found that strains/ antigenic match did not tell the whole story.
Abstract or Results, Key Passages
“The VE against A(H1N1)pdm09 was also lower for participants consecutively vaccinated during both the current and prior seasons (41%; 95% CI, 18%–57%) than for those vaccinated during the current season only (75%; 95% CI, 45%–88%)”
Keywords: effectivenessfluinfluenzaseasonal influenza vaccinevariants
Full Author List: Danuta M Skowronski, Catharine Chambers, Suzana Sabaiduc, Gaston De Serres, Anne-Luise Winter, James A Dickinson, Jonathan B Gubbay, Steven J Drews, Christine Martineau, Hugues Charest, Mel Krajden, Nathalie Bastien, Yan Li
