Lead Author: Vibeke Manniche
Original date of publication: 06/19/2025
Link: https://journals.sagepub.com/doi/10.1177/09246479251353384
Summary Context
Early research from Czech Republic indicated a significantly lower rate of successful conceptions (live birth at 9 months) among those mothers who were vaccinated. Not controlled for confounding variables but an early look at a subsequently well-documented phenomenon of menstrual and pregnancy-related issues with the mRNA platform.
Comments
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The headline is notable- a 33% reduction in the rate of successful conceptions among vaccinated women in Czech Republic. The authors admit poor access to confounding information (socioeconomic status, age, etc) which limits the depth of the analysis. They note as one possible driver the fact that they and other authors have found “a batch-dependent safety signal for the Comirnaty vaccine (Pfizer-BioNTech) in the Czech Republic, Denmark, Sweden, and the US, and the possibility of a disproportionate influence of early batches of this vaccine on SC rates remains to be investigated.”
Abstract or Results, Key Passages
During the study period, there were approximately 1,300,000 women aged 18–39 years in the Czech Republic, and the proportion of COVID-19-vaccinated women increased from January 2021 until reaching a steady state of around 70% by the end of 2021. At least from June 2021, successful conceptions per 1000 women were considerably lower for women who were vaccinated, compared to those that were unvaccinated, before SC. Furthermore, SC rates for the vaccinated group were much lower than expected based on their proportion of the total population.
Keywords: adverse eventscovid vaccinationfertilitymRNAPfizerpregnancyreproductive harmside effects
Full Author List: Vibeke Manniche, Tomáš Fürst, Max Schmeling, Jonathan D Gilthorpe, and Peter Riis Hansen
